DMSA

[Teri March]

Hello-
I’m definitely a start low go slow person.

What is your comfort level using DMSA on individuals on lots of medications – including narrow range meds like Coumadin?

Looked up drug interactions- definitely avoid the nibs and mabs, but that’s generally not my population.

Definitely use good judgement with the elderly, along with renal/hepatic disease history.

But any good advice to avoid trouble when multiple other medications are on board? Especially since it’s given every 3-4 hrs?

I looked at the chemical structures of random drugs- they pretty much all have double bonded oxygen. Just seems like we could be grabbing hold of a whole lot of things (meds) that we rather wouldn’t.

I really want to use this- but I have zero experience.
Thank you for any words of wisdom as I search for my comfort level here. I suspect big arsenic problem in my population- EWG.org says levels are >1,900x ewg’s guidelines!

Topic

[Kurt Woeller]

Teri,
The polypharmacy scenario is a real concern, particularly in the elderly. I really like low dose DMSA and have never seen any tangible problems, e.g., drug interactions, liver enzyme elevations. However, because it is a mineral chelator too it is really important to keep up with these nutrients – particularly zinc.

Have you thought about starting with supplement chelators for a few months to see how people respond, then graduate to low dose DMSA? I do not feel the every 3 to 4 hour dosing is going to interfere with anything else as far as absorption, the coumadin levels should just be checked like before anyway and adjusted if needed.

Sincerely,
Dr. Woeller

[Author]

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