Butyrate for Mold

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  • #1570

    Hi Dr Woeller,

    Do you have any opinion or experience using butyrate for mold detoxification?

    I know some probiotics produce it.

    One of my patients has exogenous mold exposure but the testing shows that she doesn’t have internal mold, just chronic exposure to something in her environment.

    What do you think?

    -MJ

Viewing 8 replies - 1 through 8 (of 8 total)
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  • #1571
    Kurt Woeller
    Keymaster

    Michael,
    I haven’t used it for mold. Try it and see if it helps.
    Dr. Woeller

    #1574

    I think I am going to stick with the current protocol first. If I am not seeing any movement, then I will try butyrate by itself.

    I am curious about the bacterial markers on this test. Her clostridia markers are coming down while the overall bacterial markers are either staying the same or improving, and she is on a very extensive, high CFU probiotic protocol. My guess is that the probiotics are contributing to butyrate production in some way; I just can’t prove it yet.

    Another interesting thing is the Propionic Acid producing probiotic I am giving her may be contributing to this in some way. Again, no proof, but it is very interesting. I have her taking some pretty interesting species, and so far we are loving the results on the tests. I just don’t know if/how these are contributing to butyrate…

    #1575
    Kurt Woeller
    Keymaster

    Michael,
    What specific benefits have you seen from propionic acid producing bacteria? Do you know anything about the biochemistry?

    Dr. Woeller

    #1576

    At this point, Dr Woeller, anything I would say would be purely speculation.

    The product I am using is Securil from Allergy Research Group. It is Propionibacterium freudenreichii, and there is very little info out there about it.

    It appears to act as a prebiotic for bifido bacteria, and possibly clostridia strains (I’m guessing). But my patient that is taking it is seeing HPHPA levels decrease to normal levels while taking it + the other probiotics/antimicrobials. But the bacterial markers are increasing slightly. And she is having positive GI results from the bifido bacteria and we are not using any prebiotic products.

    So, it seems to be of benefit. To what extent, it is too early and too small a sample size to say. But the pricing point is good and I can’t see any adverse effects, so it is worth the experiment.

    Here are some exciting things I found on the ‘net:

    “One area of intrigue surrounding this bacterium has been its potential usage as a probiotic. P. freudenreichii produces a bifidogenetic compound that aids in stimulating bifidobacterial growth.[12] On the molecular level, recent studies have indicated that the surface proteins of P. freudenreichii adhere to human intestinal cells. This binding of surface proteins is what allows for certain functions to then take place, such as modulating the release of cytokines by human intestinal cells”

    This is also the species that is found in fermented cheeses and dairy products, making it a good supplement for those who can’t have dairy.

    I have been having some success, and fun, using all these interesting species and strains of probiotics. Not many of them are very popular, but we are seeing results (GI, mostly) and no adverse reactions.

    #1577
    Kurt Woeller
    Keymaster

    Michael,
    When you mention bacteria markers are increasing. Do you mean on the OAT? Hippuric and/or DHPPA?

    Dr. Woeller

    #1578

    It’s very slight increases in

    Hippuric
    2-Hydroxyphenylacetic
    4-Hydroxybenzoic
    4-Hydroxyhippuric

    They all came down and then came back up, while the clostridia markers generally went down and the Arabinose normalized.

    I am working on a summary of the case and I am compiling the test reports for you and I will email them to you soon to take a look.

    #1579
    Kurt Woeller
    Keymaster

    Michael,
    There is an ebb and flow with these markers naturally.
    Dr. Woeller

    #1580

    Yes, agreed, but it seems like a really interesting coincidence to keep track of.

Viewing 8 replies - 1 through 8 (of 8 total)
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