NAC levels and 2 hydroxybutyric acid

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  • August 26, 2019 at 10:07 pm #1721
    Suzanne Ellison
    Member

    I have a 4 y.o. with weight loss, hair loss, and IBS symptoms…on OAT there is dysbiosis, yeast and fungal markers, all 3 oxalate markers up, lots of Krebs cycle and some fatty acid markers elevated. Even a mitochondrial marker is up.

    And she has NAC levels above the mean. … I never see this in adults who are lucky to have a very low level, it seems. In adults, is the NAC deficit due to the use by making glutathione? Folate and B12 look okay, B2 is low.

    In adults I see a high hydroxybutyric acid and a very low NAC commonly, but in this child, does a highish NAC push the system to show more 2 OHbutyric acid? mycotoxins,

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  • August 27, 2019 at 12:58 am #1723
    Kurt Woeller
    Keymaster

    Suzanne,
    The NAC could be high from using NAC, but I am assuming that is not happening here. It could be a problem in converting NAC into the glutathione pathway. Lack of ATP from mitochondrial dysfunction could contribute as well.

    There may be a polymorphism either in gamma-glutamylcysteine synthase or Glutathione Synthetase enzymes. Look up the biochemical pathways online.

    Dr. Woeller

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